Chromosome Evil 2

Chromosome Evil 2

Released Feb 2024

Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

87% positive · 270 reviews
Not yet
Released, but still in active development
Medium confidence
Active Development
Not yet
Released, but still in active development
Medium confidence
Active Development

Where to buy

Steam $19.99
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Evaluation

Chromosome Evil 2 launched out of Early Access on February 15, 2024. Since then, the developer (a two-person team at 16 BIT NIGHTS) has continued delivering meaningful updates at a sustained pace. A major overhaul arrived in April 2024 (version 1.5x, adding new weapons, ammunition types, and balance revisions), followed by a significant feature update in October 2024 (equipment transfer improvements, time acceleration, and a sandbox mode). A surprise update on January 1, 2026 added a special mission mode and a community-created map. Most recently, on February 17, 2026, the developer's partner shipped additional challenge missions accessible from the main menu, and the team invited players to submit their own community-made maps for potential inclusion in future updates. The studio is transparent about its future being focused on new projects — at least three new games are in development — but the partner responsible for Chromosome Evil 2's updates has continued to ship content independently. The developer has not announced that updates to this game are finished. The most recent update was on February 17, 2026, and the open invitation for community map submissions suggests further additions are possible. No DLC has been announced or listed for the game.
Evidence
Developer's partner shipped additional challenge missions and invited community map submissions for future inclusion in the game.
news post · Feb 17, 2026 source content shipped
high
Secret surprise update added a special mission mode and a community-created custom mission. Community members were invited to submit their own maps for potential inclusion.
news post · Jan 1, 2026 source content shipped
high

Media

Details

Publisher
S.C. 16 BIT NIGHTS S.R.L.
Achievements
10
Platform
Windows
Controller
—
Steam Deck
Playable
Players
Single-player

About this game

An ancient Lovecraftian evil has returned to earth unleashing a deadly flesh organism upon humanity.

One by one the the governments and the infrastructures of humans fell.

In the Aftermath of these events, you are part of what's left of the army and it is up to you to ensure the survival of the human species.

During combat, you take control of your strike team ensuring they will fulfill their objectives and return safely by choosing the optimal equipment and best tactical approach.

  • real-time strategy controls

  • "turn-based" possibility with active pause command mode

                                                         
As a commander, you will take control of a military convoy where you can:

  • decide the equipment of your strike team

  • assign personnel to different survival tasks

  • craft better equipment

  • research new technologies

  • choose the path you want the convoy to take

  • manage resource priority

  • train your personnel

Chapter 1 - introduction to the game lore and new game options

Chapter 2 - The journey begins, assemble your convoy

Chapter 3 - Open-World

Chapter 4 - Multiple endings + 2 different totally unique paths

Additionally, the game folder also contains a Map Editor.

                                                     Good luck Commander!

Last evaluated Jun 20, 2026
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